Olfactory receptor family 1 subfamily R member 1 pseudogene (OR1R1)

Olfactory receptor family 1 subfamily R member 1 (OR1R1) is annotated as a pseudogene in the human genome, meaning it does not encode a functional protein product. Normally, olfactory receptors are part of the large family of G protein-coupled receptors (GPCRs) in the olfactory epithelium, responsible for detecting odorant molecules and triggering neuronal responses that underlie the sense of smell. While intact olfactory receptor genes are responsible for this function, pseudogenes such as OR1R1 have lost their protein-coding potential through evolutionary mutation or deletion, and thus do not act as functional receptors in odorant signal transduction[4][1]. OR1R1 and its closely related aliases refer to a locus that includes other pseudogenes in the olfactory receptor family (for example, OR1R2P, OR1R3P, OR20A1P), which also do not produce functional receptor proteins[4]. No disease relevance, drug interactions, or utility as a therapeutic target is currently associated with this pseudogene. Key facts: - OR1R1 is not a functional receptor; it is a pseudogene in humans[4]. - No biological function, mechanism of action, or disease involvement has been attributed to OR1R1 as a molecule[4]. - Standard olfactory receptor genes that are functional (not pseudogenes) belong to the G protein-coupled receptor family and mediate odorant detection in sensory neurons[1][4].

Other names

OR1R1OR17-1OR17-01OR1R1POR1R2POR1R3POR20A1POlfactory receptor OR1R1Olfactory receptor family 1 subfamily R member 1 pseudogeneOlfactory receptor, family 1, subfamily R, member 2 pseudogeneOlfactory receptor, family 1, subfamily R, member 3 pseudogeneOlfactory receptor, family 20, subfamily A, member 1 pseudogene