Olfactory receptor family 1 subfamily S member 1 (OR1S1)

Olfactory receptor family 1 subfamily S member 1 (OR1S1) is a **G protein-coupled receptor (GPCR)** primarily expressed in the olfactory epithelium, where it interacts with odorant molecules to initiate neuronal signaling and trigger the perception of smells[3][5]. Like other olfactory receptors, OR1S1 possesses a **seven-transmembrane domain structure** typical of GPCRs and is part of the largest gene family in the human genome[3][1][5]. This gene sometimes acts as a segregating pseudogene: some individuals carry a functional allele, while others possess a non-functional variant[3]. Its primary physiological function is in the detection and discrimination of odorants, linking external environmental cues to neural sensory pathways[3][5]. There is no established role for OR1S1 in disease or pharmacology, and it is not currently associated with any therapeutically targeted drugs[3][5].

Other names

OR11-232OST034HsOR11.12.10ORL3315olfactory receptor 1S1olfactory receptor OR11-232