Olfactory receptor family 1 subfamily S member 2 (OR1S2)

Olfactory receptor family 1 subfamily S member 2 (OR1S2) is a member of the large olfactory receptor family in humans, which are responsible for the perception of odors by interacting with odorant molecules in the nose and initiating neuronal responses that lead to the sense of smell[4][5][6]. OR1S2, like all olfactory receptors, is a G protein-coupled receptor (GPCR) with a characteristic 7-transmembrane domain structure shared by many neurotransmitter and hormone receptors[4][5]. Olfactory receptors arise from single coding-exon genes and constitute the largest gene family in the human genome[4][5]. The primary role of OR1S2 is to recognize specific odorant molecules and mediate the transduction of odorant signals via a G protein-mediated pathway, initiating a downstream signaling cascade involved in olfactory perception[4][5][6]. There is no current evidence supporting a role for OR1S2 as a therapeutic target, disease biomarker, or drug-interacting protein. Key features: - Human gene symbol: OR1S2 - Not a pseudogene[2] - Located on chromosome 11[2] - 7-transmembrane GPCR structure[4][5][6] - Interacts with odorants in the olfactory epithelium but not established as a drug target - No validated disease role or therapeutic applications[4][5][6]

Other names

OR11-231HsOR11.12.9ORL3309olfactory receptor 1S2olfactory receptor OR11-231