Target intelligence / Profile preview

Olfactory receptor family 10 subfamily A member 5 (OR10A5)

Target
OR10A5
Molecular classification
G protein-coupled receptor, Receptor, Odorant receptor
01

Overview

Olfactory receptor family 10 subfamily A member 5 (OR10A5) is a protein coding gene encoding a member of the olfactory receptor family, which are G protein-coupled receptors (GPCRs) with a characteristic 7-transmembrane domain structure[1][5][6][7]. OR10A5 is expressed in the nasal olfactory epithelium, where it binds to odorant molecules to initiate a neuronal response, resulting in the perception of smell[1][5]. Olfactory receptors comprise the largest gene family in the human genome and have high sequence diversity, allowing the detection of a wide range of chemical odors[1][5][3]. Recently, olfactory receptors including OR10A5 have also been detected in nonolfactory tissues and may have uncharacterized physiological functions beyond smell[3]. OR10A5 is not currently considered a conventional drug target, and there are no approved drugs directed against it.

Other names
OR10A1OR11-403JCG6HP3Olfactory receptor 10A1Olfactory receptor 11-403Olfactory receptor-like protein JCG6olfactory receptor OR11-85olfactory receptor, family 10, subfamily A, member 1
02

Biological functions

Signal transductionSensory perception of smell (olfaction)G protein-mediated transduction of odorant signals
03

Disease associations

Other (no clear disease association as a therapeutic target; De Quervain disease has genetic association but no evidence for causality or direct role)
04

Safety considerations

Other (olfactory receptors as a class are not typical drug targets and may present challenges for selectivity and tissue accessibility)

Beyond the preview

Go deeper on Olfactory receptor family 10 subfamily A member 5 (OR10A5).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Olfactory receptor family 10 subfamily A member 5 (OR10A5).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call