Target intelligence / Profile preview

Olfactory receptor family 10 subfamily G member 2 (OR10G2)

Target
OR10G2
Molecular classification
G protein-coupled receptor, Receptor, Odorant receptor
01

Overview

Olfactory receptor family 10 subfamily G member 2 (OR10G2) is a member of the large family of olfactory receptors, which are G protein-coupled receptors (GPCRs) with a characteristic seven-transmembrane domain architecture[7][2][1]. OR10G2 is involved in the detection of odorant molecules in the nasal epithelium, participating in the sense of smell through G protein-mediated signal transduction[1][7]. While olfactory receptors as a group are mainly responsible for chemosensation, some have documented roles in nonolfactory tissues, but there is no direct evidence of extranasal functions or disease associations for OR10G2 specifically[1]. OR10G2 is considered a functional gene (not a pseudogene), found on human chromosome 14, and shows strong sequence similarity to olfactory receptors in other mammals[2]. No drugs, clinical biomarkers, or known therapeutic interventions are associated with this specific receptor.

Other names
OR14-41AE000658-BHsOR14.2.4ORL3697olfactory receptor OR14-41olfactory receptor 10G2OR10G2
02

Biological functions

Signal transductionOdorant detectionChemosensation
03

Disease associations

Other (there is no established direct disease association for OR10G2 specifically; olfactory receptors in general may be involved in extranasal processes and potentially disease states, but this is not known for OR10G2 itself)[1].

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