Target intelligence / Profile preview

Olfactory receptor family 10 subfamily G member 9 (OR10G9)

Target
OR10G9
Molecular classification
G protein-coupled receptor, Receptor, 7-transmembrane protein, Olfactory receptor
01

Overview

Olfactory receptor family 10 subfamily G member 9 (OR10G9) is a seven-transmembrane G protein-coupled receptor primarily expressed in the olfactory epithelium of the human nose. It binds odorant (smell) molecules, activating a G protein signaling cascade that ultimately leads to neuronal signaling and conscious perception of smells. Olfactory receptors like OR10G9 are encoded by single exon genes; they compose the largest gene family in the human genome and share structural features with other GPCRs involved in signal transduction. There is no evidence that OR10G9 is targeted by any therapeutic drug or is involved in non-olfactory disease processes.

Other names
Olfactory receptor 10G9OR10G9Olfactory receptor 10G10OR10G10Polfactory receptor OR11-272
02

Mechanism of action

Not applicable for approved drugs; olfactory receptors, in general, transduce extracellular signals (odorant binding) via G protein-mediated pathways

03

Biological functions

Odorant detectionSignal transduction (G protein-mediated)Sensory perception of smell
04

Disease associations

Other (no established disease association as of current knowledge; some olfactory receptors have extra-nasal roles but there is no evidence for disease involvement for OR10G9 specifically)
05

Safety considerations

None known (not a therapeutic target, not associated with notable safety concerns)
06

Interacting drugs

None known (there are currently no drugs directly targeting OR10G9)
07

Biomarkers

None established (not used as a biomarker in clinical practice or research)

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