Target intelligence / Profile preview

Olfactory receptor family 10 subfamily J member 3 (OR10J3)

Target
OR10J3
Molecular classification
G protein-coupled receptor (GPCR), Receptor, Transmembrane protein
01

Overview

Olfactory receptor family 10 subfamily J member 3 (OR10J3) is a member of the largest gene family in the human genome, the olfactory receptors, which function as G protein-coupled receptors mediating the detection of odorants in the nose and initiating the neuronal response responsible for smell perception[1][3][12]. Like other olfactory receptors, it has a characteristic seven-transmembrane domain structure, similar to many hormone and neurotransmitter receptors[1]. In humans, the OR10J3 gene is frequently annotated as a pseudogene because of truncation or loss of protein function in certain species or individuals[3]. The encoded (or predicted) protein is involved in the binding and recognition of odorant molecules, facilitating signal transduction through GPCR-mediated pathways[1][12]. No drugs or disease associations are documented, nor is this receptor a known clinical biomarker or therapeutic target.

Other names
Olfactory receptor 10J3OR10J3OR10J3POlfactory receptor, family 10, subfamily J, member 3Olfactory receptor OR1-25 pseudogeneOR1-25
02

Mechanism of action

Not applicable; no drugs are known to target this molecule.

03

Biological functions

Odorant bindingOlfactory receptor activity/detection of chemicals involved in sensory perception of smellSignal transduction (via G protein-mediated signaling)
04

Disease associations

None established; olfactory receptors are not generally implicated in major diseases such as cancer, inflammation, etc., and this specific pseudogene does not have documented disease associations
05

Safety considerations

None notable; not currently a drug target.
06

Interacting drugs

None documented in the available sources. Drugs do not typically target olfactory receptors for therapeutic purposes.
07

Biomarkers

None known; not used in clinical biomarker panels.

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