Olfactory receptor family 11 subfamily G member 1 pseudogene (OR11G1P)

Olfactory receptor family 11 subfamily G member 1 pseudogene (OR11G1P) is a human gene classified as a pseudogene, meaning it is derived from an ancestral olfactory receptor gene but has acquired mutations (such as nonsense or frameshift changes) that prevent production of a functional protein. The olfactory receptor gene family is the largest in the human genome, encoding G protein-coupled receptors that detect odorant molecules, but many members, including OR11G1P, are pseudogenes. Pseudogenes generally lack biological function and are not considered relevant drug targets. While rare reports in other organisms (notably certain Drosophila species) describe functional "pseudo-pseudogenes" that are translated via readthrough mechanisms, there is no compelling evidence that OR11G1P encodes a functional receptor in humans. Note: OR11G1P is routinely listed in genomic catalogs with functional olfactory receptors, but is specifically marked as a pseudogene in authoritative sources. Information applies strictly to humans; functional rescue of olfactory receptor pseudogenes is documented only in non-human models like Drosophila and is not relevant for OR11G1P. Its only relevance is to genomic annotation, not to therapeutic targeting or drug development.

Other names

OR11G1POR14-30HsOR14.1.24PORL3709

Not applicable—no functional protein produced; no known mechanisms relevant to therapeutic action