Olfactory receptor family 11 subfamily H member 2 (OR11H2)

Olfactory receptor family 11 subfamily H member 2 (OR11H2) is a member of the olfactory receptor gene family, which encodes G protein-coupled receptors (GPCRs) characterized by their seven transmembrane domains. Olfactory receptors are primarily responsible for detecting odorant molecules in the nose and initiating neuronal signals that result in the perception of smell. Like most olfactory receptors, OR11H2 is part of one of the largest protein families encoded in the human genome. The precise ligand specificity, function, and clinical relevance of the human OR11H2 protein are largely uncharacterized, and there is no evidence that this specific olfactory receptor serves as a therapeutic target or interacts with any approved drugs. Several alternative names and pseudogene annotations (e.g., OR11H2P) are associated with this gene, suggesting potential pseudogene status or variable annotation in different sources. OR11H2 appears to correspond to a less-studied or pseudogene-annotated member of the olfactory receptor family, and there is little to no evidence for its function as an expressed, functional protein in humans. It is not recognized as a therapeutic target; clinical or pharmacological targeting information is unavailable. Some aliases in the list (e.g., OR11H2P, C14orf15, OR11H8P) are pseudogenes or alternative loci, indicating possible ambiguity or misannotation. This target is not considered an established therapeutic or clinical target (no disease roles, drugs, or clinical biomarkers). There is ambiguity due to pseudogene annotations and overlapping aliases, making it a problematic entry if used for drug discovery or therapeutic profiling. The target has no known, characterized disease association or small molecule modulators. Olfactory receptor family 11 subfamily H member 2 (OR11H2) is an olfactory GPCR of unclear functional or therapeutic relevance, likely a pseudogene or non-expressed gene in humans, without interactions with drugs or biomarkers, and should not be considered a valid therapeutic target according to available evidence.

Other names

Olfactory receptor 11H2OR11H2C14orf15OR11H2POlfactory receptor OR14-1OR11H13OR11H8Pseven transmembrane helix receptor