Olfactory receptor family 13 subfamily C member 6 pseudogene (OR13C6P)

Olfactory receptor family 13 subfamily C member 6 pseudogene (OR13C6P) is classified as a pseudogene, meaning it is a DNA sequence derived from an ancestral olfactory receptor gene but contains mutations or truncations that prevent it from encoding a functional protein[1][3][4]. Olfactory receptors are part of the large family of G protein-coupled receptors (GPCRs) responsible for detecting odorant molecules and initiating the perception of smell, but pseudogenes such as OR13C6P lack functional activity due to genetic disruption. Although olfactory receptor pseudogenes are abundant due to low evolutionary pressure to retain all potential olfactory receptor functions, there is no evidence that OR13C6P produces functional protein or participates in cellular signaling. It has no known therapeutic relevance, does not interact with drugs, is not used as a biomarker, and poses no safety concerns for clinical research[1][2][3][4]. If it were functional, it would share structural similarity to other olfactory GPCRs, but as a pseudogene, this does not apply. - The canonical name is validated by multiple databases and matches the family/nomenclature conventions for human olfactory receptor pseudogenes[1][2][4]. - This is not a valid therapeutic target since it is not functional; it is a genomically annotated pseudogene and not a receptor capable of ligand binding or signal transduction[1][3][4]. - There is some naming confusion due to overlap with other pseudogene entries (such as “Olfactory receptor, family 13, subfamily C, member 7 pseudogene” and “OR37B”), but the primary identifier is “Olfactory receptor family 13 subfamily C member 6 pseudogene” (OR13C6P); other aliases refer to similar or related pseudogenes and should be harmonized accordingly[1][2][4]. - No mechanism of action, biomarkers, or disease roles are described in the literature as it is functionless as a protein or gene product[1][3][4].

Other names

Putative olfactory receptor 13C6Olfactory receptor, family 13, subfamily C, member 6 pseudogeneOlfactory receptor, family 13, subfamily C, member 7 pseudogenePutative olfactory receptor 13C7Putative olfactory receptor ENSP00000348552OR37B