Target intelligence / Profile preview

Olfactory receptor family 13 subfamily D member 1 (OR13D1)

Target
OR13D1
Molecular classification
Receptor, G protein-coupled receptor (GPCR), Seven-transmembrane domain protein
01

Overview

Olfactory receptor family 13 subfamily D member 1 (OR13D1) is a protein coding gene in humans that encodes a member of the large olfactory receptor family, which is responsible for the initial detection of odorant molecules in the nose. These receptors activate a neuronal signaling cascade, triggering the perception of smell. OR13D1 is a G protein-coupled receptor, characterized by a seven-transmembrane domain structure common to many neurotransmitter and hormone receptors. This gene belongs to the largest gene family in the human genome and operates by converting external chemical stimuli (odorants) into corresponding intracellular signals via G protein-mediated pathways[1][2][4][10]. There is no evidence of direct pharmacological modulation, biomarker usage, or disease association specific to OR13D1.

Other names
OR13D1Olfactory receptor 13D1Olfactory receptor OR9-15OR9-15olfactory receptor family 13 subfamily D member 1
02

Mechanism of action

G protein-mediated signal transduction upon odorant binding (general mechanism for olfactory GPCRs but no drug mechanisms are described for this target)

03

Biological functions

Olfactory receptor activityG protein-coupled receptor activityDetection of odorant moleculesInitiation of neuronal response for smell perception
04

Disease associations

Other (No direct disease association is reported; olfactory receptors generally may be implicated in anosmia or altered olfaction, but no disease mechanism is documented for OR13D1 specifically)
05

Safety considerations

None known
06

Interacting drugs

None known
07

Biomarkers

None known

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