Olfactory receptor family 14 subfamily A member 16 (OR14A16)

Olfactory receptor family 14 subfamily A member 16 (OR14A16) is a **G protein-coupled receptor (GPCR)** expressed in humans, encoded by the OR14A16 gene[1][2][5][9][10]. OR14A16 participates in **olfaction** by interacting with odorant molecules in the nose, initiating a neuronal response that triggers the perception of smell[1][5][10]. Structurally, it belongs to the large olfactory receptor family and possesses the characteristic **7-transmembrane domain** found in many neurotransmitter and hormone receptors[1][5][9][10]. While the principal function is odorant signal recognition and transduction, OR14A16 and related olfactory receptors have also been detected in non-olfactory tissues, and there is some evidence associating OR14A16 with prostate cancer, though its broader physiological and pathophysiological roles remain under investigation[5][7]. There are no known drugs currently targeting OR14A16, and it is not established as a therapeutic target in clinical practice[5].

Other names

OR5AT1Olfactory receptor 14A16Olfactory receptor 5AT1Olfactory receptor OR1-45Olfactory receptor, family 5, subfamily AT, member 1olfactory receptor OR1-45