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Target intelligence / Profile preview
Olfactory receptor family 14 subfamily J member 1 (OR14J1)
- Target
- OR14J1
- Molecular classification
- G protein-coupled receptor, Receptor, Olfactory receptor
01
Overview
Olfactory receptor family 14 subfamily J member 1 (OR14J1) is a protein-coding gene that encodes an olfactory receptor responsible for detecting odorant molecules in the nose, initiating neuronal response and perception of smell. OR14J1 is part of the large olfactory receptor family, which are G protein-coupled receptors (GPCRs) characterized by seven transmembrane domains. These receptors mediate odorant signal transduction via G protein mechanisms. OR14J1 has aliases such as OR5U1 and OR6-25 and is primarily known for its role in olfactory signaling pathways. There is limited evidence linking this receptor to disease (a reported association with dissociative amnesia), and it is not known to interact with any drugs or serve as a biomarker. No safety concerns are documented for this molecule, which is not considered a therapeutic drug target but instead functions mainly in sensory signal processing.
- Other names
- OR5U1OR6-25Olfactory receptor 5U1Olfactory receptor OR6-25hs6M1-28Hs6M1-28bA150A6.4
02
Biological functions
Odorant recognitionSignal transduction via G protein-coupling
03
Disease associations
Dissociative amnesia (reported association)Other (no major disease role documented)
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