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Olfactory receptor family 14 subfamily K member 1 is a member of the olfactory receptor gene family, which is the largest in the human genome[1][3]. These receptors are G protein-coupled, possess seven transmembrane domains, and are responsible for detecting odorant molecules in the nose, initiating neuronal responses that trigger the perception of smell[1][3][4][5]. Olfactory receptors are highly diverse, each recognizing different odorants, and work together to facilitate the sense of smell[1][4]. While primarily expressed in the nasal olfactory epithelium, some receptors are found in extranasal tissues, contributing to broader physiological processes and potentially disease mechanisms[5].
Not applicable for direct drugs (see above); general mechanism is G protein-mediated transduction of odorant signals
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