Target intelligence / Profile preview

Olfactory receptor family 2 subfamily A member 14 (OR2A14)

Target
OR2A14
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor
01

Overview

Olfactory receptor family 2 subfamily A member 14 (OR2A14) is a protein expressed in the olfactory epithelium, where it acts as a receptor for odorant molecules in the nose and initiates a neuronal response that triggers the perception of smell. OR2A14 belongs to the large olfactory receptor family, which are G protein-coupled receptors (GPCRs) characterized by a 7-transmembrane domain structure, and is encoded by a single coding-exon gene. This family of receptors is the largest gene family in the human genome, and their primary recognized function is the mediation of olfactory signals[1][3][5]. There are no confirmed roles for OR2A14 in major diseases, no interacting drugs, and it is not considered a therapeutic drug target outside of research related to olfaction.

Other names
Olfactory receptor 2A14OR2A14POR2A6OST182Olfactory receptor 2A6Olfactory receptor OR7-12olfactory receptor, family 2, subfamily A, member 14 pseudogeneolfactory receptor, family 2, subfamily A, member 6
02

Biological functions

Signal transductionRecognition of odorant moleculesSensory perception of smell
03

Disease associations

Other (there is no current evidence for a direct role in major human diseases)

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