Olfactory receptor family 2 subfamily A member 2 (OR2A2)

Olfactory receptor family 2 subfamily A member 2 (OR2A2) is a member of the large olfactory receptor gene family in humans. OR2A2 encodes a G protein-coupled receptor (GPCR) with seven transmembrane domains, primarily expressed in the olfactory epithelium, where it detects odorant molecules and initiates a neural response for the perception of smell[1][2][3]. Olfactory receptors, including OR2A2, share structural features with other GPCRs, including conserved motifs across their seven transmembrane helices. These receptors generally bind a variety of odorants, which can trigger conformational changes resulting in G protein activation and neuronal signaling[2]. While most olfactory receptors, including OR2A2, are not established therapeutic targets and have limited disease association, there is emerging research into possible roles in non-olfactory tissues, although no clear drug interactions or disease biomarker roles are defined for OR2A2[1][2][3].

Other names

Olfactory receptor 2A2OR2A2OR2A17POR2A2POST008Olfactory receptor 2A17Olfactory receptor OR7-11OR7-11olfactory receptor, family 2, subfamily A, member 17 pseudogeneolfactory receptor, family 2, subfamily A, member 2 pseudogene

Not applicable (no drugs are known to target this receptor; standard function involves activation by odorant molecules, which trigger G protein-coupled signaling in olfactory sensory neurons[1][2][3])