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Target intelligence / Profile preview
Olfactory receptor family 2 subfamily AP member 1 (OR2AP1)
- Target
- OR2AP1
- Molecular classification
- G protein-coupled receptor, Receptor, Seven transmembrane domain protein
01
Overview
Olfactory receptor family 2 subfamily AP member 1 (OR2AP1) is a protein-coding gene that encodes an odorant receptor. This receptor is responsible for the detection of odorant molecules in the nasal epithelium, playing a key role in the initiation of a neuronal response that leads to the perception of smell. OR2AP1 is part of the large G protein-coupled receptor (GPCR) superfamily, specifically the seven-transmembrane helix GPCRs. Olfactory receptors are the largest family of genes in the human genome, each typically recognizing a range of structurally related odorants and facilitating diversity in olfactory perception. There are no known therapeutic drugs or clinical biomarkers directly associated with this specific receptor, and its primary function remains the sensory detection of odorants[1][2][4].
- Other names
- Olfactory receptor OR12-9Olfactory receptor 2AP1Olfactory receptor, family 2, subfamily AP, member 1Seven transmembrane helix receptorOR2AP1POlfactory receptor, family 2, subfamily AP, member 1 pseudogene
02
Mechanism of action
Endogenous function as a GPCR transducing odorant signals
03
Biological functions
Signal transductionSensory perception (specifically, smell/olfaction)
04
Disease associations
Other (e.g., minor associations with ciliary dyskinesia, but not a major disease gene)
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