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Olfactory receptor family 2 subfamily AS member 1 pseudogene (OR2AS1P)
- Target
- OR2AS1P
- Molecular classification
- Pseudogene, Olfactory receptor pseudogene, G protein-coupled receptor (GPCR) pseudogene (by homology to functional olfactory receptors[1][2])
01
Overview
Olfactory receptor family 2 subfamily AS member 1 pseudogene (OR2AS1P) is a genomic sequence in humans annotated as a pseudogene within the large family of olfactory receptors[3]. Olfactory receptors are typically G protein-coupled receptors (GPCRs) involved in the detection of odorants, but pseudogenes such as OR2AS1P do not encode functional proteins due to mutations or loss of coding capacity[2]. Human olfactory receptor pseudogenes are numerous and reflect evolutionary redundancy or mutations in genes no longer needed for fitness[2]. Unlike some pseudogenes, there are no known regulatory, functional, or pathological roles for OR2AS1P, and it is not considered a therapeutic target in pharmaceutical or biomarker research[2][3].
- Other names
- OR2AS1POlfactory receptor, family 2, subfamily AS, member 1 pseudogeneHuman OR2AS1P (81473)AKR1B1P2 (less direct; see search result context[3])
02
Mechanism of action
None applicable
03
Biological functions
None (pseudogene, generally considered non-functional)[2]No confirmed direct role in signal transduction or perception, unlike functional olfactory receptors.
04
Disease associations
None established (no disease association due to lack of protein function)[2]Unlike some pseudogenes, OR2AS1P has not been implicated in regulatory or disease processes.
05
Safety considerations
None (does not encode a functional protein and is not targeted therapeutically)
06
Interacting drugs
None (no known drugs interact with OR2AS1P; pseudogenes do not code for active proteins or druggable sites)[2]
07
Biomarkers
None (not used as a biomarker for patient selection or disease monitoring)
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