Target intelligence / Profile preview

Olfactory receptor family 2 subfamily B member 4 pseudogene (OR2B4P)

Target
OR2B4P
Molecular classification
Pseudogene, G protein-coupled receptor family (by homology), Olfactory receptor (by sequence similarity)
01

Overview

Olfactory receptor family 2 subfamily B member 4 pseudogene (OR2B4P) is annotated as a non-functional member of the human olfactory receptor gene family. Olfactory receptors are typically G protein-coupled receptors (GPCRs) that mediate odor detection in the nose, but pseudogenes like OR2B4P do not encode functional receptor proteins in most humans[5][1]. While some olfactory receptor pseudogenes in other species (or occasionally in humans due to rare genetic variations) can occasionally retain or reacquire function, there is no experimental evidence that OR2B4P is functional or druggable in humans[5][2][3]. As a member of the largest mammalian gene family, OR2B4P represents an evolutionary remnant of olfactory receptor diversification, but it is not considered a therapeutic target and has no established biological or clinical significance.

Other names
hs6M1-22OR2B4POlfactory receptor, family 2, subfamily B, member 4 pseudogene
02

Mechanism of action

None known. (No drug mechanism is described or predicted for this gene product.)

03

Biological functions

No established biological function in humans as it is a pseudogene.
04

Disease associations

No established direct role in human disease. As a pseudogene, there is no evidence of disease association.

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