Olfactory receptor family 2 subfamily L member 2 (OR2L2)

Olfactory receptor family 2 subfamily L member 2 (OR2L2) is a G protein-coupled receptor expressed in the olfactory epithelium, responsible for detecting odorant molecules in the nose and initiating neuronal signaling that leads to the perception of smell. Like other olfactory receptors, OR2L2 is a member of the large class A GPCR family, encoded by a single coding exon, and possesses a characteristic 7-transmembrane domain structure shared with other neurotransmitter and hormone receptors. OR2L2 is involved in the recognition and G protein-mediated transduction of odorant signals but is not a validated therapeutic or drug target. There is no evidence for direct involvement in common human diseases, and there are no known drug interactions or biomarker uses for this specific receptor. Note: Some aliases correspond to predicted genes or pseudogenes, which is common among olfactory receptor nomenclature; OR2L2 itself is considered a protein-coding gene. Other similar names may denote closely related, but distinct, family members or genomic loci.

Other names

Olfactory receptor 2L2OR2L12OR2L4PHTPCRH07HSHTPCRH07olfactory receptor 2L12olfactory receptor 2L4Olfactory receptor OR1-48 pseudogeneolfactory receptor, family 2, subfamily L, member 12olfactory receptor, family 2, subfamily L, member 4 pseudogeneOR1-48

N/A (not a therapeutic drug target; mechanism is endogenous odorant ligand binding and G-protein activation)