Olfactory receptor family 2 subfamily L member 6 pseudogene (OR2L6P)

OR2L6P is a pseudogene belonging to the olfactory receptor family 2, subfamily L, member 6. As a pseudogene, it represents a non-functional DNA sequence that has evolved from what was originally a protein-coding olfactory receptor gene[1][3][4]. Olfactory receptors are typically members of the G protein-coupled receptor (GPCR) family that interact with odorant molecules in the nose to initiate neuronal responses triggering smell perception[1]. However, OR2L6P has accumulated mutations that have rendered it non-functional, which is common in olfactory receptor families due to low selection pressures to maintain receptors that may be functionally redundant or detect odors no longer relevant for species fitness[2]. The olfactory receptor gene family represents the largest gene family in the genome, and many members have become pseudogenes over evolutionary time[1]. While some pseudogenes in other receptor families have been found to undergo translational readthrough and maintain function (termed "pseudo-pseudogenes"), there is no evidence that OR2L6P retains any functional capacity[2][5]. It is catalogued with the gene ID 81465 and is available for research purposes through various molecular biology suppliers[3][4].

Other names

OR2L6Polfactory receptor family 2 subfamily L member 6 pseudogene

None (non-functional pseudogene)