Target intelligence / Profile preview

Olfactory receptor family 2 subfamily T member 29 (OR2T29)

Target
OR2T29
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor
01

Overview

Olfactory receptor family 2 subfamily T member 29 (OR2T29) is a member of the large olfactory receptor family, which are G protein-coupled receptors (GPCRs) responsible for detection of odorant molecules in the nose, initiating a neuronal response that triggers the perception of smell[3][8][4][1]. Like other olfactory receptors, OR2T29 is encoded by a single coding-exon gene and features the characteristic 7-transmembrane domain structure shared by many neurotransmitter and hormone receptors[3][1]. Olfactory receptors represent the largest gene family in the human genome, with around 400 functional genes. These receptors are primarily expressed in the nasal olfactory epithelium[1][3][4][7], although recent studies suggest some expression in nonolfactory tissues with possible, but poorly understood, physiological roles[4]. There is no evidence supporting OR2T29 as a therapeutic, diagnostic, or biomarker target, nor are there any approved drugs known to specifically interact with this receptor. Its established function is restricted to sensory transduction of smell[3][7][8].

Other names
Olfactory receptor 2T29OR2T29O2T29_HUMAN (UniProt)OR2T29 gene (GeneCards)
02

Biological functions

Sensory perception of smellDetection of chemical stimulus (involved in sensory perception of smell)Signal transduction
03

Disease associations

Other (no well-established roles in disease or as a direct disease driver)

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