Olfactory receptor family 2 subfamily W member 4 pseudogene (OR2W4P)

Olfactory receptor family 2 subfamily W member 4 pseudogene (OR2W4P) is a human gene classified as a pseudogene; it displays sequence homology with functional olfactory receptors, which are G protein-coupled receptors involved in odor detection in the nose. Unlike functional olfactory receptors, OR2W4P is not believed to encode a functional protein, and there is no evidence for its participation in canonical olfactory signal transduction or any biological pathway. It is not considered a therapeutic target, nor is it involved in disease mechanisms or targeted by drugs. The presence of olfactory receptor pseudogenes is common in the human genome because selection pressure to maintain all olfactory receptor functions has been low during primate evolution, leading to many being disabled by mutations[1][3][4][6]. Note: Because OR2W4P is a *pseudogene*, it does not encode an active protein receptor and should not be considered an actionable or functional drug target. There are no clinical, biomarker, or safety considerations relevant to this gene in therapeutic contexts[1][3][4][6].

Other names

OR2W4P