Olfactory receptor family 2 subfamily Y member 1 (OR2Y1)

Olfactory receptor family 2 subfamily Y member 1 (OR2Y1) is a protein-coding gene that encodes an olfactory receptor belonging to the large family of G protein-coupled receptors (GPCRs)[1][3]. These receptors are responsible for the recognition of odorant molecules in the nose, initiating a neuronal response that results in the perception of smell[1]. OR2Y1 and other olfactory receptors have a seven-transmembrane domain structure, characteristic of the GPCR superfamily[1]. The primary molecular function of OR2Y1 is olfactory transduction through G protein-mediated signaling mechanisms in the nasal olfactory epithelium[3]. There is increasing evidence that some olfactory receptors may have non-olfactory roles in extranasal tissues, but no such roles are specifically established for OR2Y1 to date[3][5].\n\nNo drugs are currently known to selectively target OR2Y1, and it is not widely recognized as a therapeutic drug target. There is also no known direct association with specific diseases, safety concerns, or use as a biomarker. OR2Y1 is considered a valid molecular target for basic research in sensory biology but lacks established pharmacological or clinical relevance beyond olfactory signaling[1][3].

Other names

Olfactory receptor 2Y1OR2Y1Olfactory receptor OR5-2OR5-2olfactory receptor 2Y1olfactory receptor OR5-2