Olfactory receptor family 4 subfamily A member 2 pseudogene (OR4A2P)

Olfactory receptor family 4 subfamily A member 2 pseudogene (OR4A2P) is classified as a pseudogene in the human genome[2]. While olfactory receptors are typically G protein-coupled receptors involved in the perception of smells by binding odorant molecules and triggering neuronal responses[1][2], pseudogenes like OR4A2P are generally non-functional due to accumulated sequence mutations, such as frame-shifts or premature stop codons, and do not produce active receptor protein[2][3]. These pseudogenes are prevalent in olfactory receptor families, reflecting evolutionary processes and low selection pressure for maintaining redundant receptors[3]. As a pseudogene, OR4A2P is not considered a therapeutic target, does not have established biological functions or disease roles, and lacks known drug interactions or utility as a biomarker. There is no safety concern or mechanism of drug action related to this entity. Its classification as a pseudogene makes it non-functional and not relevant for therapeutic modulation or direct disease association[2][3].

Other names

OR4A2PHGNC:15159NCBI Gene:390133Ensembl: ENSG00000227547HORDE: OR4A2PGC11U990554GC11M051461GC11M051308[2]