Olfactory receptor family 4 subfamily A member 46 pseudogene (OR4A46P)

Olfactory receptor family 4 subfamily A member 46 pseudogene (OR4A46P) is a human pseudogene belonging to the large olfactory receptor gene family, which encodes G protein-coupled receptors involved in recognizing odorant molecules in the nose and initiating a neuronal response for smell perception. In humans, a significant fraction of olfactory receptor loci have lost coding potential through mutations and are classified as pseudogenes[3][6]. OR4A46P does not produce a functional receptor protein and has no known physiological or pharmacological activity. Pseudogenes in general may play limited regulatory roles at the RNA level, but no specific function or drug relevance has been attributed to OR4A46P[2][6]. There is no evidence for its involvement in diseases, nor is it considered a target for therapies, diagnostic biomarkers, or drugs. Note: Some olfactory receptor pseudogenes in other species (such as Drosophila) may retain unexpected functional properties or regulatory roles due to translational read-through[2], but no such function is known for human OR4A46P. In summary: OR4A46P is a non-functional, annotated pseudogene in the human olfactory receptor family, with no known roles in signaling, drug interaction, or disease, and no therapeutic or safety implications[3][6].

Other names

OR4A46P