Olfactory receptor family 4 subfamily C member 4 pseudogene (OR4C4P)

Olfactory receptor family 4 subfamily C member 4 pseudogene (OR4C4P, also known as OR4C47P) is a human gene classified as a pseudogene, derived from the olfactory receptor family, specifically within subfamily C. In its functional form, olfactory receptors are part of the G protein-coupled receptor (GPCR) superfamily, which are responsible for detecting odorant molecules and initiating neuronal signals related to smell. These genes are typically single-exon, encode proteins with a 7-transmembrane domain structure, and comprise the largest gene family in the human genome[1][3][5]. As a pseudogene, OR4C4P contains sequence similarity to functional olfactory receptor genes but is not expected to produce a functional protein due to debilitating mutations or disruptions within the coding sequence. Pseudogenes like OR4C4P generally lack known biological function, are not endogenous drug targets, and do not play established disease roles, serve as biomarkers, or have recognized therapeutic implications[2][4]. The parent gene's archetype—olfactory receptors—belong to the Class A (Rhodopsin-like) GPCRs, whose canonical functions are involved in sensory signal transduction of odorants[1][5]. However, OR4C4P itself is genomically defined as non-functional.

Other names

OR4C4POR4C47P