Target intelligence / Profile preview

Olfactory receptor family 4 subfamily C member 46 (OR4C46)

Target
OR4C46
Molecular classification
G protein-coupled receptor, Receptor, Transmembrane protein
01

Overview

Olfactory receptor family 4 subfamily C member 46 (OR4C46) is a member of the olfactory receptor family of proteins responsible for the detection of odorant molecules in the nose, thereby initiating a neuronal response that leads to the perception of smell[3][8][9]. Like other olfactory receptors, OR4C46 is a G protein-coupled receptor (GPCR) and is characterized by a 7-transmembrane domain structure shared with many neurotransmitter and hormone receptors[3][9]. The gene encoding this receptor arises from a single coding exon, typical of olfactory receptor genes, which together constitute the largest gene family in the human genome[3]. OR4C46 is involved in the olfactory signaling pathway but does not have a known or established role as a therapeutic target, nor is it associated with any drugs or used as a biomarker in clinical practice[3][8][9]. Notes: - OR4C46 is not currently considered a therapeutic target; it is primarily studied in the context of olfaction and has no established disease relevance or drug interactions as of the current scientific literature[3][8][9]. - Most olfactory receptors, including OR4C46, remain functionally uncharacterized outside of their primary sensory role, and no specific ligands or modulatory drugs have been identified for this receptor[7][3].

Other names
Olfactory receptor 4C46OR4C46olfactory receptor family 4 subfamily C member 46
02

Mechanism of action

Not applicable (No known therapeutic agents targeting this receptor)

03

Biological functions

Signal transductionRecognition and G protein-mediated transduction of odorant signals
04

Disease associations

Other (Not documented to have direct roles in major therapeutic disease areas as of current knowledge)
05

Safety considerations

None documented; not a therapeutic target

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