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Target intelligence / Profile preview
Olfactory receptor family 4 subfamily D member 10 (OR4D10)
- Target
- OR4D10
- Molecular classification
- G protein-coupled receptor (GPCR), Seven transmembrane helix receptor, Odorant receptor, Receptor
01
Overview
Olfactory receptor family 4 subfamily D member 10 (OR4D10) is a protein-coding gene in humans responsible for encoding a G protein-coupled receptor involved in olfactory signal transduction. OR4D10 is localized in the olfactory epithelium, where it detects odorant molecules and initiates the neuronal cascade that leads to the perception of smell. This receptor features the classic seven transmembrane domain structure found in all GPCRs, highlighting its evolutionary relation to hormone and neurotransmitter receptors. The gene is part of the largest gene family in the human genome, dedicated to the recognition and discrimination of odorants. There is no evidence for disease association or interaction with drugs, nor is it used as a clinical biomarker or therapeutic target; its function is specialized for sensory biology.
- Other names
- Olfactory receptor 4D10OR4D10OR4D10POST711Olfactory receptor OR11-251OR11-251Olfactory receptor, family 4, subfamily D, member 10 pseudogene
02
Mechanism of action
G protein-mediated signal transduction in response to odorant molecule binding
03
Biological functions
Signal transduction (odorant-triggered)Sensory perception of smell (olfactory perception)
04
Disease associations
None established; minor reference to Carboxypeptidase N deficiency association, but not a validated disease roleOther
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