Olfactory receptor family 4 subfamily D member 9 (OR4D9)

Olfactory receptor family 4 subfamily D member 9 (OR4D9) is a member of the olfactory receptor gene family, which comprises a large group of genes encoding G protein-coupled receptors responsible for detecting odorant molecules in the nose, initiating a neuronal response that leads to odor perception[5][1][2]. Olfactory receptors are characterized by a seven-transmembrane domain structure and typically have a single coding exon[5][1][2]. While olfactory receptors as a class are involved in signal transduction by activating G proteins in response to odorant binding, OR4D9 specifically is listed as a pseudogene in some databases, indicating it may not produce a functional protein in humans[5][3]. No drugs are known to specifically target OR4D9, nor has it been established as a therapeutic target in any disease context[5][3].\n\nNote: This target is problematic because some databases (e.g., GeneCards, Ensembl) list it as a pseudogene, implying lack of protein-coding function in humans[5][3]. This disqualifies it as a classic therapeutic target and merits the flag in the is_incorrect field.\n\nSummary of key points\n- The canonical full name is “Olfactory receptor family 4 subfamily D member 9,” with “OR4D9” as the canonical abbreviation.\n- OR4D9 is classified under G protein-coupled receptors involved in olfactory signaling.\n- It is not a known therapeutic target, drug target, or disease biomarker, and no drugs are documented to interact with it.\n- It is likely a pseudogene in humans, so it is not functionally expressed as a protein[5][3].\n- The principal role of the gene family is odorant detection, but OR4D9 itself probably does not have a discernible physiological or disease-related function in humans[5][3].

Other names

Olfactory receptor OR11-253OR11-253Olfactory receptor 4D9Olfactory receptor, family 4, subfamily D, member 9 pseudogene