Olfactory receptor family 4 subfamily F member 17 (OR4F17)

Olfactory receptor family 4 subfamily F member 17 (OR4F17) is a protein coding gene that encodes an olfactory receptor, which is a member of the large G protein-coupled receptor (GPCR) superfamily[1][5]. These receptors are responsible for the recognition of odorant molecules in the nasal epithelium, initiating a neuronal response that triggers the perception of smell[1][2][3]. Like other olfactory receptors, OR4F17 has a characteristic 7-transmembrane domain structure and mediates its effects by G protein signaling[1][2][3][5]. Olfactory receptor genes constitute the largest gene family in the human genome[1][7]. OR4F17 is primarily involved in sensory signal transduction but may have broader physiological roles, as emerging studies reveal ectopic expression of olfactory receptors in non-olfactory tissues, including cancers[7]. Specific disease association for OR4F17 is limited, but it is mapped as associated with Cardiofaciocutaneous Syndrome 4[1]. There is currently no established role for OR4F17 as a therapeutic target, interacting drug, or clinical biomarker.

Other names

OR4F11POR4F18OR4F19OR4F5Olfactory receptor 4F17Olfactory receptor 4F11Olfactory receptor 4F18Olfactory receptor 4F19olfactory receptor, family 4, subfamily F, member 11 pseudogeneolfactory receptor, family 4, subfamily F, member 19