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Target intelligence / Profile preview
Olfactory receptor family 4 subfamily K member 1 (OR4K1)
- Target
- OR4K1
- Molecular classification
- G protein-coupled receptor, Receptor
01
Overview
Olfactory receptor family 4 subfamily K member 1 (OR4K1) is a member of the olfactory receptor gene family, which encodes for proteins that recognize odorant molecules in the nasal epithelium and initiate neuronal responses responsible for the perception of smell. OR4K1 is a G protein-coupled receptor (GPCR) with the characteristic seven-transmembrane domain structure shared by many neurotransmitter and hormone receptors. Its main role is facilitating G protein-mediated transduction of odorant signals. The gene is located on chromosome 14 and is part of the largest gene family in the human genome[1][2][3][4][6][7][8].
- Other names
- Olfactory receptor 4K1OR4K1Olfactory receptor OR14-19OR14-19
02
Mechanism of action
No specific mechanism of action for drugs targeting OR4K1 has been reported as no interacting drugs are currently identified.
03
Biological functions
Signal transductionRecognition of odorant moleculesG protein-mediated transduction of odorant signals
04
Disease associations
Delusional disorderGlycogen storage disease III (as reported by association, though direct mechanistic involvement is not established)
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