Target intelligence / Profile preview

Olfactory receptor family 4 subfamily K member 13 (OR4K13)

Target
OR4K13
Molecular classification
G protein-coupled receptor, Receptor, 7-transmembrane receptor
01

Overview

Olfactory receptor family 4 subfamily K member 13 (OR4K13) is a G protein-coupled receptor (GPCR) encoded by the OR4K13 gene in humans[1][2][4]. This receptor is expressed in the olfactory epithelium where it binds specific odorant molecules in the nose, triggering a neuronal response that leads to the perception of smell[1][4]. Like other olfactory receptors, OR4K13 possesses a 7-transmembrane domain structure and is part of the largest gene family in the human genome[1][4]. Its primary biological function is in the detection and transduction of odorant signals, playing no known direct role in disease or as a drug target[1][2][4]. **Notes:** - OR4K13 is not considered a therapeutic or pharmacological target; no drugs, mechanisms, or biomarker roles are documented for this receptor in the context of disease or therapy[1][4][6]. - Aliases and synonyms listed in various databases are included for comprehensive cross-referencing[2][5][8]. - No known safety concerns or therapeutic challenges are specific for this molecule, as its biological function is dedicated to olfaction, with no established links to common pathologies or adverse reactions[1][4][6].

Other names
OR14-27HsOR14.1.18ORL3689Olfactory receptor 4K13Olfactory receptor OR14-27
02

Biological functions

Signal transductionNeuronal response to odorantsOlfactory perception
03

Disease associations

Other (no direct disease association as odorant receptors are not typically implicated in common human diseases)

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