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Target intelligence / Profile preview
Olfactory receptor family 4 subfamily K member 2 (OR4K2)
- Target
- OR4K2
- Molecular classification
- G protein-coupled receptor, Receptor
01
Overview
Olfactory receptor family 4 subfamily K member 2 (OR4K2) is a member of the olfactory receptor family, which are G protein-coupled receptors (GPCRs) responsible for the recognition and transduction of odorant signals in the nose, ultimately triggering the perception of smell. These receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors. The olfactory receptor gene family is the largest in the human genome, and each receptor typically arises from a single coding-exon gene. While OR4K2 participates in the olfactory signaling pathway, it has limited characterized roles outside the olfactory system and is not recognized as a drug target or biomarker in clinical medicine[1][2][7][8].
- Other names
- Olfactory receptor 4K2OR4K2Olfactory receptor OR14-15OR14-15
02
Biological functions
Signal transductionOdorant recognitionG protein-mediated transduction of odorant signals
03
Disease associations
Other (some associations to Schizophrenia 3 and Delusional Disorder; no strong evidence for a therapeutic disease role)
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