Target intelligence / Profile preview

Olfactory receptor family 4 subfamily N member 4 (OR4N4)

Target
OR4N4
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor, Rhodopsin-like receptor
01

Overview

Olfactory receptor family 4 subfamily N member 4 (OR4N4) is a human protein that belongs to the olfactory receptor family, specifically the subfamily N, member 4. Olfactory receptors, including OR4N4, are G protein-coupled receptors (GPCRs) characterized by a 7-transmembrane domain structure. They are responsible for detecting odorant molecules in the nose, which initiates a neuronal response leading to the perception of smell. OR4N4 is encoded by a single coding-exon gene and, like other members of its family, mediates G protein-mediated transduction of odorant signals. The olfactory receptor family is the largest gene family in the human genome. OR4N4 itself has limited evidence for involvement in disease, with a rare association reported with Mayer-Rokitansky-Kuster-Hauser Syndrome Type 1. There are no known therapeutic drugs or biomarker roles for this receptor at present[1][2][3][4][5][7][8][9].

Other names
Olfactory receptor 4N4OR4N4Olfactory receptor OR15-1Olfactory receptor OR15-5OR15-1OR15-5
02

Biological functions

Signal transductionOdorant detection (olfactory signaling)G protein-coupled receptor activity
03

Disease associations

Mayer-Rokitansky-Kuster-Hauser Syndrome Type 1

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