Target intelligence / Profile preview

Olfactory receptor family 4 subfamily P member 4 (OR4P4)

Target
OR4P4
Molecular classification
G protein-coupled receptor, Receptor, Transmembrane protein
01

Overview

Olfactory receptor family 4 subfamily P member 4 (OR4P4) is a human G protein-coupled receptor involved in detecting odorant molecules in the nose, thereby initiating signal transduction for the sense of smell[1][3][5][10]. Like other olfactory receptors, it possesses a 7-transmembrane domain structure and is part of the largest gene family in the human genome[1][5]. OR4P4 is encoded by a single-exon gene on chromosome 11 and is not classified as a pseudogene; it is considered functional in humans[2][10]. Its primary biological role is in the olfactory pathway, with no established clinical significance beyond sensory perception, and it is not currently a drug development target or disease biomarker[5][10].

Other names
Olfactory receptor 4P4OR4P3POlfactory receptor 4P3HsOR11.11.18ORL3311Olfactory receptor, family 4, subfamily P, member 3 pseudogene
02

Mechanism of action

not a known pharmacological target, so no defined mechanisms of action for drugs

03

Biological functions

Signal transductionOdorant recognitionInitiation of neuronal response to smell
04

Disease associations

Other (no strong direct evidence for major disease implication, but some associative reports [minor, e.g. linked as a gene in certain GWAS like transverse colon cancer, but not as a major therapeutic target][5])

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