Target intelligence / Profile preview

Olfactory receptor family 5 subfamily AC member 2 (OR5AC2)

Target
OR5AC2
Molecular classification
G protein-coupled receptor, Receptor, Transmembrane protein
01

Overview

Olfactory receptor family 5 subfamily AC member 2 (OR5AC2) is a human protein-coding gene belonging to the large family of olfactory receptors, which are specialized G protein-coupled receptors (GPCRs) involved in the detection of odorant molecules in the nose[6][5][2][4]. These receptors initiate a neuronal response that triggers the perception of smell, sharing a characteristic 7-transmembrane domain structure with many other neurotransmitter and hormone receptors[6][5]. As part of the olfactory signaling pathway, OR5AC2 contributes to the molecular mechanisms underlying human olfaction[6][5]. While genetic associations with certain diseases such as cataract and prostate cancer have been reported, OR5AC2 itself is not considered a direct pharmacological or therapeutic target and does not currently have recognized roles in drug action, biomarker use, or adverse safety profiles[6].

Other names
Olfactory receptor 5AC2OR5AC2HSA1O5AC2_HUMAN [UniProt notation][6]
02

Mechanism of action

Not applicable. There are no drugs known to specifically target this receptor, nor is it a standard therapeutic target.

03

Biological functions

Signal transductionOdorant recognitionG protein-mediated transduction of odorant signals
04

Disease associations

Cataract (Cataract 21, Multiple Types)[6]Prostate cancer[6]Other (no widely established direct therapeutic or disease-specific role for this receptor)

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