Target intelligence / Profile preview

Olfactory receptor family 5 subfamily AU member 1 (OR5AU1)

Target
OR5AU1
Molecular classification
G protein-coupled receptor, Odorant receptor, 7-transmembrane receptor
01

Overview

Olfactory receptor family 5 subfamily AU member 1 (OR5AU1) is a human odorant receptor and a member of the large olfactory receptor (OR) gene family. Like other olfactory receptors, it is a G protein-coupled receptor (GPCR) characterized by a 7-transmembrane domain structure shared with many neurotransmitter and hormone receptors. OR5AU1 is responsible for recognizing specific odorant molecules in the nasal cavity, initiating a neuronal response that leads to the perception of smell. Olfactory receptors function through G protein-mediated transduction of odorant signals. While OR5AU1 is principally associated with the sense of smell, the olfactory receptor family has been detected in some nonolfactory tissues and implicated in a wide range of physiological processes, but specific nonolfactory roles for OR5AU1 are unreported. There are no known drugs or therapeutic agents targeting this receptor, and it is not currently used as a biomarker or associated with notable safety concerns.

Other names
Olfactory receptor OR14-38OR14-38HsOR14.2.1ORL3340olfactory receptor 5AU1
02

Biological functions

Signal transductionOdorant recognitionSensory perception of smell
03

Disease associations

Other (Potential nonolfactory functions and possible association with disease, but no established roles in major disease categories)

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