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Olfactory receptor family 5 subfamily BH member 1 pseudogene (OR5BH1P)

Target
OR5BH1P
Molecular classification
Pseudogene, Olfactory receptor family (pseudogene form), G protein-coupled receptor (ancestral/family classification)
01

Overview

Olfactory receptor family 5 subfamily BH member 1 pseudogene (OR5BH1P) is a nonfunctional genomic DNA segment classified as a pseudogene in humans. It belongs to the large olfactory receptor gene family, whose members encode G protein-coupled receptors responsible for detecting odorant molecules. However, as a pseudogene, OR5BH1P contains mutations or disruptions that prevent it from encoding a functional protein. It does not contribute to olfactory signal transduction or other known biological processes, nor is it currently considered a therapeutic target or associated with disease or drug response[1][3][5][9].\n\nKey notes:\n- The gene is annotated as a *pseudogene*, meaning it does not code for a functional protein product[5][9].\n- Although related to the **olfactory receptor family** (G protein-coupled receptor superfamily), it is itself **nonfunctional**[5][9].\n- It is **not a therapeutic target** and has no known pharmacological relevance[5].\n- Aliases include **OR5BH2P** and Horizon Genome Resource identifies others such as **HsORX.1.3P** and **ORL4079**[9].\n- There is **no evidence for disease association, drug interaction, or biomarker status** for this pseudogene[5][9].\n- Related olfactory receptor pseudogenes are frequently found in the human genome due to the loss of function from evolutionary mutations[11].\n\nNo incorrectly spelled names are noted, though care should be taken not to confuse functional olfactory receptors with their pseudogene counterparts.

Other names
OR5BH2Polfactory receptor, family 5, subfamily BH, member 2 pseudogeneHsORX.1.3PORL4079
02

Biological functions

No functional protein product (as a pseudogene)Ancestral: Signal transduction (for functional olfactory receptors)

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