Olfactory receptor family 5 subfamily BK member 1 pseudogene (OR5BK1P)

Olfactory receptor family 5 subfamily BK member 1 pseudogene (OR5BK1P) is a human pseudogene belonging to the olfactory receptor gene family, specifically classified in family 5, subfamily BK[1][2][3]. Olfactory receptors are normally part of a large group of G protein-coupled receptors (GPCRs) that detect odorant molecules and mediate the perception of smell via signal transduction in olfactory sensory neurons. OR5BK1P, however, is annotated as a *pseudogene*—meaning it contains sequence variants or mutations (such as premature stop codons, frameshifts, etc.) that are predicted to render it non-functional, so it does not encode an active receptor protein. As with other processed olfactory receptor pseudogenes, no protein product or physiological function has been reported, and there is no evidence linking it to therapeutic drug targeting, disease association, or biomarker utility[2][6]. Additional clarification: - “Pseudogene” indicates this gene sequence is not believed to produce a functional protein, due to disruptive mutations[1][2][6]. - It is not considered a therapeutic target, nor does it have any known pharmacological or pathophysiological relevance. - Olfactory receptor gene families in humans contain many pseudogenes, reflecting relaxed selective pressure for functional expression of all possible odorant detection receptors[6]. Summary of conventions & curation: - “Olfactory receptor family 5 subfamily BK member 1 pseudogene” is the established canonical name. - Abbreviation "OR5BK1P" is universally used. - No interacting drugs, mechanisms of action, or safety/biomarker information. - “Pseudogene” is the primary molecular classification; these genes are typically not functional and are excluded from therapeutic target databases. - Notation, nomenclature, and function assignment are consistent with conventions of the Human Olfactory Receptor Data Explorer and GeneCards[1][2].

Other names

HsOR12.3.2PORL3665