Olfactory receptor family 5 subfamily F member 1 (OR5F1)

Olfactory receptor family 5 subfamily F member 1 (OR5F1) is a member of the large family of olfactory receptors within the G protein-coupled receptor (GPCR) superfamily. Like other olfactory receptors, OR5F1 has a canonical seven-transmembrane domain structure and is encoded by a single-exon gene. These receptors are responsible for the recognition and G protein-mediated transduction of odorant signals in the nose, initiating neuronal responses that lead to the perception of smell. OR5F1 is part of the largest gene family in the human genome, and its nomenclature is species-specific. Diseases associated with OR5F1 include Kallmann syndrome, though the receptor's principal role is in olfactory signaling[3][5]. **Notes:** - There is no evidence in the provided sources or public domain indicating known drugs, biomarkers, or substantial therapeutic applications for OR5F1, nor are there notable safety concerns specifically reported for this receptor[3][5]. - The protein is a typical olfactory receptor, playing a role mainly in primary odor detection and signal transduction; not generally considered a direct therapeutic target in classical pharmacology contexts[5]. - All key structural and functional attributes are consistent across the primary databases and literature cited[3][5].

Other names

Olfactory receptor 5F1OR5F1OR11-10Olfactory receptor 11-10Olfactory receptor OR11-167OR5F1_HUMANO95221