Olfactory receptor family 5 subfamily H member 5 pseudogene (OR5H5P)

**Olfactory receptor family 5 subfamily H member 5 pseudogene (OR5H5P)** is a human gene classified as a pseudogene, meaning it is a segment of DNA that resembles a functional olfactory receptor gene but has lost the ability to encode a functional protein due to disabling mutations such as premature stop codons or frameshifts[6][5]. Olfactory receptors are members of the class A (rhodopsin-like) family of G protein-coupled receptors and are normally expressed in olfactory sensory neurons to mediate the sense of smell[3][5]. However, OR5H5P no longer encodes a functional protein and there is no evidence for its translation, biological activity, or disease relevance[5][2]. As with many olfactory receptor pseudogenes, it represents a remnant of gene family evolution in primates and does not represent a therapeutic target or biomarker. **Key points**: - OR5H5P is a **pseudogene** of an olfactory receptor, with sequence similarity to functional G protein-coupled olfactory receptors, but it does not produce an active receptor[6][5]. - It is not considered a **therapeutic target** and has no associated **drugs**, **biological functions**, or **safety concerns**[5]. - It has various **aliases** and is part of the large olfactory receptor gene family, most of which are non-functional in humans due to the accumulation of loss-of-function mutations[3][5].

Other names

OR3-3olfactory receptor OR3-3 pseudogeneolfactory receptor, family 5, subfamily H, member 14 pseudogeneOR5H5P

Not applicable (non-coding pseudogene)