Target intelligence / Profile preview

Olfactory receptor family 5 subfamily M member 1 (OR5M1)

Target
OR5M1
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor
01

Overview

Olfactory receptor family 5 subfamily M member 1 (OR5M1) is a member of the large family of olfactory receptors, which are G protein-coupled receptors (GPCRs) responsible for the recognition and G protein-mediated transduction of odorant signals in the nose[3][7]. OR5M1, like all olfactory receptors, has a canonical seven-transmembrane domain structure typical of GPCRs and is encoded by a single exon gene[3][7]. These receptors detect odorant molecules, leading to the activation of a neuronal response that underlies the sense of smell. Olfactory receptors constitute the largest gene family in the human genome. While olfactory receptor proteins collectively are essential for olfaction, individual family members such as OR5M1 do not have documented roles in disease or established pharmacological targeting[3][7].

Other names
Olfactory receptor 5M1OST050Olfactory receptor OR11-208seven transmembrane helix receptorOR11-208
02

Mechanism of action

No drugs directly acting on this receptor; mechanism for endogenous ligands involves G protein-coupled signal transduction upon odorant binding

03

Biological functions

Signal transductionOdorant recognition (olfactory signal transduction)
04

Disease associations

Other (no well-established direct links to human disease, mainly involved in smell perception)

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