Target intelligence / Profile preview

Olfactory receptor family 5 subfamily M member 10 (OR5M10)

Target
OR5M10
Molecular classification
G protein-coupled receptor, Receptor, 7-transmembrane domain protein
01

Overview

Olfactory receptor family 5 subfamily M member 10 (OR5M10) is a seven-transmembrane G protein-coupled receptor that belongs to the largest gene family in the human genome. It is responsible for recognizing specific odorant molecules in the nose and initiating a G protein-mediated signal transduction pathway, leading to neuronal activation and the perception of smell. OR5M10 is encoded by the OR5M10 gene, which arises from single coding-exon genes typical of olfactory receptors. Members of the olfactory receptor family share structural similarities with other GPCRs and may have additional, still poorly understood roles in nonolfactory tissues[1][3][7][8].

Other names
Olfactory receptor 5M10OR5M10Olfactory receptor OR11-207OR11-207
02

Biological functions

Signal transductionOdorant recognition (initiation of neuronal responses that trigger the perception of smell)
03

Disease associations

Other (Potential extranasal effects, nonolfactory physiological processes implied by recent research[7]; direct disease association rare, but there are database entries mentioning "C1 Inhibitor Deficiency" and "Three M Syndrome 1"—however, supporting evidence for direct causal involvement is lacking[8].)

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