Target intelligence / Profile preview

Olfactory receptor family 5 subfamily T member 1 (OR5T1)

Target
OR5T1
Molecular classification
G protein-coupled receptor (GPCR), Receptor, 7-transmembrane domain protein
01

Overview

Olfactory receptor family 5 subfamily T member 1 (OR5T1) is a member of the olfactory receptor family, which comprises G protein-coupled receptors (GPCRs) responsible for detecting odorant molecules in the nasal epithelium and initiating neuronal responses that lead to the perception of smell. OR5T1 shares the typical seven-transmembrane domain architecture with other GPCRs and is encoded by a single-exon gene. While OR5T1 is cataloged in protein and gene databases as a functional receptor, there is limited experimental evidence about its specific odorant ligands and physiological role compared to other olfactory receptors. OR5T1 does not have documented involvement in human disease, clinical drug targeting, or recognized biomarker status. Notes on nomenclature and context: - The "pseudogene" designation (OR5T1P) was previously used but is not considered canonical for the currently recognized protein-coding gene. - OR5T1 follows human olfactory receptor nomenclature conventions, and its classification as a GPCR is based on sequence and predicted structure, not direct pharmacological targeting or disease relevance.

Other names
Olfactory receptor 5T1OR5T1OR5T1POlfactory receptor OR11-179OR11-179Family 5, subfamily T, member 1Olfactory receptor, family 5, subfamily T, member 1 pseudogene
02

Mechanism of action

Not applicable, since there are no known drugs targeting this receptor. For olfactory receptors generally, mechanism involves G protein-mediated signal transduction upon odorant binding

03

Biological functions

Signal transductionOdorant recognitionInitiation of neuronal response to smells (olfactory perception)
04

Disease associations

Other. There are no documented roles in disease such as cancer, neurodegeneration, or infection. Olfactory receptors can sometimes be ectopically expressed in some cancers or tissues, but there is no evidence for OR5T1's involvement
05

Safety considerations

None notable. No known safety concerns or therapeutic challenges have been described for targeting OR5T1
06

Interacting drugs

None known. There are no approved drugs or clinical agents identified that target OR5T1 specifically. Olfactory receptors are not usual therapeutic targets
07

Biomarkers

None. OR5T1 is not used as a biomarker for disease monitoring or patient selection

Beyond the preview

Go deeper on Olfactory receptor family 5 subfamily T member 1 (OR5T1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Olfactory receptor family 5 subfamily T member 1 (OR5T1).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call