Olfactory receptor family 51 subfamily F member 1 (OR51F1)

Olfactory receptor family 51 subfamily F member 1 (OR51F1) is part of the largest family of G protein-coupled receptors, primarily responsible for odorant detection in the human nasal epithelium. Like other olfactory receptors, it typically displays a seven-transmembrane domain structure that interacts with G proteins to transduce chemical signals from inhaled odorants into neuronal activity, triggering the sensation of smell. The OR51F1 gene is a segregating pseudogene: in some individuals the allele encodes a functional protein, while in others it encodes a non-functional product. As a member of the Class I subfamily, it is likely specialized for detection of hydrophilic odorants. This receptor is not associated with any currently defined disease, is not targeted by drugs, and is primarily relevant for sensory perception.

Other names

OR51F1Olfactory receptor 51F1OR51F1POR11-21olfactory receptor OR11-21 pseudogeneolfactory receptor, family 51, subfamily F, member 1 pseudogene