Target intelligence / Profile preview

Olfactory receptor family 51 subfamily G member 2 (OR51G2)

Target
OR51G2
Molecular classification
Receptor, G protein-coupled receptor (GPCR), Olfactory receptor
01

Overview

Olfactory receptor family 51 subfamily G member 2 (OR51G2) is a member of the olfactory receptor family and encodes a G protein-coupled receptor (GPCR) expressed primarily in the sensory neurons of the nasal olfactory epithelium[4]. Like other olfactory receptors, OR51G2 has a seven-transmembrane domain architecture and is responsible for recognizing specific odorant molecules (typically volatile compounds) and initiating the signal transduction cascade that results in the perception of smell. Olfactory receptors such as OR51G2 function via G protein-mediated pathways, transmitting chemical signals from odorants to the brain through neuronal activation. OR51G2 is one of approximately 400 functional human olfactory receptor genes, constituting the largest protein family in the genome[4]. Summary of limitations: There is no evidence that OR51G2 is directly targeted by approved drugs, nor is it a known drug target or biomarker in clinical use as of this writing. The description and classification represent the most current and accurate knowledge based on structural, functional, and genomic data.

Other names
OR51G2Olfactory receptor 51G2O51G2
02

Biological functions

Signal transductionOlfactory signalingSensory perception of smell
03

Disease associations

Other

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