Target intelligence / Profile preview

Olfactory receptor family 51 subfamily Q member 1 (OR51Q1)

Target
OR51Q1
Molecular classification
G protein-coupled receptor, Receptor, Olfactory receptor
01

Overview

Olfactory receptor family 51 subfamily Q member 1 (OR51Q1) is a protein-coding gene in humans comprising a seven-transmembrane domain typical of G protein-coupled receptors. Like other olfactory receptors, OR51Q1 interacts with odorant molecules in the nose, triggering neuronal signals that initiate the perception of smell. These receptors form the largest gene family in the genome, each potentially recognizing different odorants. Olfactory receptors can share structural similarity with neurotransmitter and hormone receptors, but their primary biological function is chemosensory signal transduction for olfaction. No therapeutic drugs are known to interact with OR51Q1, and it is not considered a current therapeutic target in drug development. Some olfactory receptors, in general, may have roles in non-olfactory tissue, but no well-established extranasal or disease roles are documented for OR51Q1 specifically[1][5][7].

Other names
Olfactory receptor 51Q1Olfactory receptor, family 51, subfamily Q, member 1OR51Q1
02

Biological functions

Signal transductionRecognition of odorant moleculesInitiation of neuronal response for smell perception
03

Disease associations

Other (no well-established direct disease roles; one database notes a speculative association with pancreatic squamous cell carcinoma, but this is not a well-supported disease mechanism)

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