Target intelligence / Profile preview

Olfactory receptor family 52 subfamily A member 4 pseudogene (OR52A4P)

Target
OR52A4P
Molecular classification
Pseudogene, G protein-coupled receptor (pseudogene family), Olfactory receptor pseudogene
01

Overview

OR52A4P (Olfactory receptor family 52 subfamily A member 4 pseudogene) is classified as a **pseudogene** and is not believed to encode a functional olfactory receptor protein in humans[3]. While functional olfactory receptors are G protein-coupled receptors (GPCRs) involved in odor detection in the nasal epithelium, OR52A4P has a C-terminal frameshift that prevents it from producing a typical, full-length, functional receptor protein[3]. As a pseudogene, OR52A4P does not participate in canonical biological signaling or odorant recognition, nor is it a direct target for therapeutic drugs or clinical biomarkers. The family of olfactory receptor genes (including many pseudogenes) represents the largest receptor family in the human genome, but this particular member is inactive and not implicated in disease nor targeted by any known pharmaceuticals[3]. **Key distinctions**: - OR52A4P is a pseudogene, not a functional protein-coding gene. - While biologically related to the olfactory receptor gene family, it does not play a direct role in olfaction or signal transduction due to its sequence disruption. - It is not considered a drug target, nor are any drugs or biomarkers linked to it[3]. If you require structured data for a functional olfactory receptor (such as OR52E2 or consensus OR52), additional information may be available for those genes, which are implicated as class A GPCRs involved in odorant signal transduction[1][4].

Other names
Olfactory receptor 52A4OR52A4putative olfactory receptor 52A4OR52A4P
02

Biological functions

Other (not functional; see description)

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