Target intelligence / Profile preview

Olfactory receptor family 52 subfamily L member 2 pseudogene (OR52L2P)

Target
OR52L2P
Molecular classification
G protein-coupled receptor, Olfactory receptor, Pseudogene
01

Overview

OR52L2P, or Olfactory receptor family 52 subfamily L member 2 pseudogene, is annotated as a **pseudogene** within the human genome and is part of the large family of olfactory receptors, which are typically G protein-coupled receptors (GPCRs) with a seven transmembrane domain structure[3]. While canonical olfactory receptors detect odorant molecules and mediate the sense of smell via G protein-transduced signaling, pseudogenes such as OR52L2P are considered non-functional and are not known to translate into active proteins[3]. There is no evidence supporting a therapeutic or disease-related role, nor association with any drugs, biomarkers, or clinical safety concerns. Its sequence similarity to olfactory receptors reflects a likely ancestral function in olfaction, but current data do not support its role as a functional or druggable protein target in humans[3].

Other names
Putative olfactory receptor 52L2OR52L2Olfactory receptor OR11-74Olfactory receptor 52L2Seven transmembrane helix receptor
02

Biological functions

Other (Potential olfactory signaling; note: as a pseudogene, no confirmed function in humans)
03

Disease associations

Other (No established disease association)

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